IMPORTANT DRUGS FOR HEALTHY LIFE-1

Hello world this is  my first post about drugs for healthy life . I  hope this post important all the people for their daily life.


PANADEINE-  paracetamol, codeine phosphate.

 

  
DESCRIPTION-    Each tablet contains paracetamol ph Eur 500                                  mg and codeine phosphate ph Eur 8 mg.

ACTIONS  : Pharmacology: - The analgesic and antipyretic  actions  of paracetamol are similar to those of the salicylates. Analgesia is mediated peripherally and also centrally, whereas antipyresis is produced by a central action on the hypothalamic  regulator center. Panadeine also contains a small amount of codeine, an opiate with analegesic  and antitussive actions,to provide additional pain relief.

INDICATIONS  : Relief of painful disorders, eg: headche, dysmenorrhea,  conditions involving musculoskeletal pain,myalgias , and neuralgias . Conditions accompanied  by discomfort and fever, eg the common cold and viral infections. Analgesic after dental work and tooth extractions.
    
 DOSAGE& ADMINISTRATION: Adults :1-2 tabs, 3 or 4 times daily.Do not exceed 8 tabs in 24 hrs.
              Children 7-12 years 1/2 -1 tab , 3 or 4 times daily,up to 4 tabs (2 g paracetamol ) . Do not exceed 4  tabs in 24 hrs . Not recommended for children < 7 years.

OVERDOSAGE: Serious toxicity is rare following    administration Serious toxicity is rare following  of recommended does of paracetamol.How ever, when  taken in large amounts, hepatic necrosis many result. Clinical and laboratory evidence of hepatotoxicity  may be delayed for up to a week with the small quantity of codeine present in panadeine , overdosage is unlikely. How ever , symptoms , if they did occur, would be opiate-like . In all cases of suspected overdose, prompt medical attention is critical adults as well as for children even if one does not notice any signs or symptoms.     

         

PRECAUTIONS:   Codeine may be habit-forming .Use panadeine with caution in patients with acute abdominal conditions and in other special risk patients.(eg, those with head injury, increased intracranial presure or with Addison's disease).

Patients should be advised that panadeine contains codeine, which can produce sedation in some individuals. Do not take Panadeine for pain >10 days unless directed by a doctor. If pain persists or worsens, if new symptoms occur, or if redness of swelling is present ,consult a doctor because these could be signs of a serious condition. If store throat is server , persists for>2 days , is accompained or follow by fever, headache, rash, nausea, or vomiting , consult a doctor promptly.

Effects on the Ability to Drive  or operate Machineries ;codeine may impair the mental and/ or physical abilities required for the performance of potentially hazardous tasks, eg driving a car or operating machinery. 

ADVERSE REACTIONS: The most frequently observed adverse reactions to codeine include lighteadedness,dizziness, sedation,nausea and vomiting , but these generally occur with a dose larger than that in panadeine.

  When taken in recommended doses, paracetamol is usually free from adverse effects. skin reactions , eg urticaria, have been described rarely.

INTERACTIONS:  patients receiving other CNS depressants, including alcohol, may exhibit additive CNS effects.